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The SAFE Port Act of 2006 directs the Domestic Nuclear Detection Office (DNDO) to develop technical capability standards and recommended standard operating procedures for nuclear and radiation detection equipment. In collaboration with the National Institute of Science and Technology, DNDO provides leadership in the development of national standards relating to nuclear detection technologies.

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Technology alone will not prevent an act of nuclear terrorism, and success in the nuclear security mission requires more than the deployment of new technologies and equipment. It also requires the integration of programs, organizations, training, exercises and operational support across many layers of jurisdiction, including international, federal, state, local, tribal and territorial.

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Research and development is critical to enabling the success of the Department of Homeland Security (DHS) and its nuclear security mission partners. The Domestic Nuclear Detection Office (DNDO) leads the Department's efforts in the development of near- and long-term radiological and nuclear detection capabilities.
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The transit and border layer (Trans-Border) is composed of transit to the U.S. from a foreign port of departure or non-port of departure, as well as passing through the U.S. border prior to entering the U.S. interior. This represents the last opportunity to detect radiological or nuclear materials prior to their arrival onto U.S. territory, and initiatives in this layer emphasize maritime domain awareness related to preventive radiological/nuclear detection.

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Working in close cooperation with its nuclear security stakeholders, the Department of Homeland Security has developed the Global Nuclear Detection Architecture (GNDA).
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The nation’s success in preventing nuclear terrorism is a result of the close collaboration between the Department and its international, federal, state, local, tribal, and territorial partners.

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The Department of Homeland Security (DHS) conducts tests to evaluate the performance of radiological and nuclear detection systems (to include technology components, algorithms and materials), at specialized facilities, laboratories, or operational venues. The Domestic Nuclear Detection Office leads the Department’s efforts to test and evaluate these technologies.
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The National Strategy for Chemical, Biological, Radiological, Nuclear, and Explosives (CBRNE) Standards lays out the federal vision and goals to achieve a comprehensive structure for coordination, establishment, and implementation of CBRNE equipment standards by 2020.

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The Graduated Rad/Nuc Detector Evaluation and Reporting (GRaDER) Program evaluates commercial off-the-shelf (COTS) Rad/Nuc detection equipment against national standards adopted by the Department of Homeland Security.

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