Evaluation of Disinfectant Efficacy against SARS-CoV-2 in Simulated Respiratory Fluids Fact Sheet

This study was conducted to examine the efficacy of eight disinfectants that are representative of major classes of disinfectants found in liquid cleaners to reduce the viral load on contaminated surfaces. Virus was suspended in simulated respiratory fluid, either simulated saliva (saliva) or simulated lung fluid (SLF), and deposited onto stainless steel coupons and either disinfected when still wet or allowed to dry prior to disinfection for the prescribed contact time for each disinfectant. No pre-cleaning or wiping was done during these tests to model a worst case scenario where a user applies disinfectant onto a contaminated surface and walks away. It would be anticipated that pre-cleaning or wiping of the surface would increase the efficacy of the disinfectants. From this study and results produced, this information may assist in informing ongoing control and prevention strategies for the COVID-19 pandemic, and confirm the utility of select products listed on the US EPA-curated list of disinfectants with claims for use against SARS-CoV-2.