The COVID-19 pandemic offers a rare opportunity to conduct real-time research in support of identifying future incident planning and research and development (R&D) priorities for radiological or nuclear (R/N) emergency response. National Urban Security Technology Laboratory (NUSTL) has partnered with the Federal Emergency Management Agency and the U.S. Department of Energy (DOE) National Nuclear Security Administration (NNSA) to document lessons from the COVID-19 pandemic that can be applied to an R/N incident.